Gee Brain, what do you want to do tonight? „
“ The same thing we do every night, Pinky.
Try to take over the world! „
The Brain is a small laboratory mouse who is trying to conquer the world. He has an oversized brain, and is very knowledgeable. However, his attempts to conquer the world always fail, mostly because of his partner and only friend Pinky, who is very silly and always messes up the plan. But The Brain doesn't let that bring him down, and by next night he will have a new trick up his sleeve. He is the Primary Antagonist in animaniacs.
Both Brain and Pinky are laboratory mice who underwent an experiment to make them rational. The experiment had different results on each of them, turning Brain into a super genius, while Pinky also becomes sentient but incredibly stupid. Brain then decided he would use his superior knowledge to take over the world and make it a better place using his intellect. He conviced Pinky to aid him in his plans, and the two of them try a new plan to achieve world domination every night.
Brain's angry face
Brain is a genius with a calm and overconfident personality. He almost never loses his cool, even when Pinky commits stupid errors that mess his plans completely (though he does often display clear annoyance). He also seems to be egocentric. Despite his plans, he truely believes that he can make the world a better place, will never resort to murder to accomplish his goals and deep down he does care about Pinky. There are also some world domination plans even he won't attempt as they are sick even to him: for instance, he was unwilling to use a plan involving selling cigarettes to children. Brain's good intentions are highlighted with his rival called Snowball, a hamster who also planned to conquer the world, but who is far more evil and cruel. Brain is disgusted by Snowball's methods and will stop at nothing to prevent him from taking over the world.
Villains possibly inspired by The Brain
Brain Gremlin: Both have a highly developed brain due to mutations caused by science experiments, and plan to use their knowledge to gain control of the world.
Zim: Both have completely idiotic henchmen who aren't evil at all (Zim's henchman is GIR). Both are also doomed to be enternally foiled.
Dr. Heinz Doofenshmirtz
Digimon Emperor: Both are evil geniuses, and both abuse their minion both verbally and physically (Digimon Emperor's is Wormmon whilst Brain's is Pinky).